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Cardiac Markers

NT-proBNP

Normal range < 125 (age < 75); < 450 if older pg/mL (< 125 ng/L SI). Specimen: Plasma or serum.

Also known as: N-terminal proBNP.

< 125 (age < 75); < 450 if older pg/mLReference range

Reference range

This result is reported qualitatively or as a one-sided threshold rather than a two-sided numeric band.

SpecimenPlasma or serum
Conventional range< 125 (age < 75); < 450 if older pg/mL
SI range< 125 ng/L
Conversion factor×1 (conventional → SI)
PanelCardiac Markers

Convert any NT-proBNP result between units on the unit converter.

What is the normal range for NT-proBNP?

The standard teaching reference range for NT-proBNP is < 125 (age < 75); < 450 if older pg/mL in conventional units, or < 125 ng/L in SI units. This value is measured in plasma or serum.

Source: Adult reference values compiled from Pagana & Pagana, Mosby's Diagnostic and Laboratory Test Reference, and Fischbach & Dunning, A Manual of Laboratory and Diagnostic Tests. Reference ranges vary by laboratory, method, age, sex, and population — always use the range printed on the actual result.

Above the range

Common causes of a high NT-proBNP

  • Heart failure
  • Renal impairment
  • Advanced age

Below the range

Common causes of a low NT-proBNP

  • Obesity

At the bedside

Nursing considerations

  • Thresholds rise with age; a low value makes heart failure unlikely.

Study aid

Your notes on NT-proBNP

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