Iron Studies

Total Iron-Binding Capacity (TIBC)

Normal range 240–450 µg/dL (43–81 µmol/L SI). Specimen: Serum.

Also known as: iron-binding capacity.

240–450 µg/dLReference range

Reference range

Conventionalµg/dL

240450

SIµmol/L

4381

Specimen	Serum
Conventional range	240–450 µg/dL
SI range	43–81 µmol/L
Conversion factor	×0.179 (conventional → SI)
Panel	Iron Studies

Convert any Total Iron-Binding Capacity (TIBC) result between units on the unit converter.

What is the normal range for Total Iron-Binding Capacity (TIBC)?

The standard teaching reference range for Total Iron-Binding Capacity (TIBC) is 240–450 µg/dL in conventional units, or 43–81 µmol/L in SI units. This value is measured in serum.

Source: Adult reference values compiled from Pagana & Pagana, Mosby's Diagnostic and Laboratory Test Reference, and Fischbach & Dunning, A Manual of Laboratory and Diagnostic Tests. Reference ranges vary by laboratory, method, age, sex, and population — always use the range printed on the actual result.

Above the range

Common causes of a high Total Iron-Binding Capacity (TIBC)

Iron-deficiency anemia
Pregnancy
Estrogen therapy

Below the range

Common causes of a low Total Iron-Binding Capacity (TIBC)

Iron overload
Chronic disease / inflammation
Malnutrition

At the bedside

Nursing considerations

Rises in iron deficiency as the body makes more transferrin to capture iron.

Study aid

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Same panel

More Iron Studies tests

Ferritin12–300 ng/mL Serum Iron60–170 µg/dL Transferrin200–360 mg/dL Transferrin Saturation20–50 %