All tests · Coagulation Studies

Coagulation Studies

Activated Partial Thromboplastin Time (aPTT)

Normal range 25–35 seconds. Specimen: Plasma (sodium citrate).

Also known as: PTT, partial thromboplastin time.

25–35 secondsCritical: read below

Reference range

Conventionalseconds
2535
SpecimenPlasma (sodium citrate)
Conventional range25–35 seconds
SI range25–35 seconds
Conversion factor×1 (conventional → SI)
Critical value> 70 seconds (bleeding risk)
PanelCoagulation Studies

Convert any Activated Partial Thromboplastin Time (aPTT) result between units on the unit converter.

What is the normal range for Activated Partial Thromboplastin Time (aPTT)?

The standard teaching reference range for Activated Partial Thromboplastin Time (aPTT) is 25–35 seconds. This value is measured in plasma (sodium citrate).

A commonly taught critical (panic) value is > 70 seconds (bleeding risk). Critical results are reported to the provider immediately under your facility's policy.

Source: Adult reference values compiled from Pagana & Pagana, Mosby's Diagnostic and Laboratory Test Reference, and Fischbach & Dunning, A Manual of Laboratory and Diagnostic Tests. Reference ranges vary by laboratory, method, age, sex, and population — always use the range printed on the actual result.

Above the range

Common causes of a high Activated Partial Thromboplastin Time (aPTT)

  • Unfractionated heparin therapy
  • Hemophilia
  • von Willebrand disease
  • DIC / liver disease

Below the range

Common causes of a low Activated Partial Thromboplastin Time (aPTT)

  • Early DIC (hypercoagulable phase)

At the bedside

Nursing considerations

  • Monitors unfractionated heparin; therapeutic is roughly 1.5–2.5× control.
  • Keep protamine sulfate available as the heparin antidote.

Study aid

Your notes on Activated Partial Thromboplastin Time (aPTT)

Same panel

More Coagulation Studies tests