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Coagulation Studies

Fibrinogen

Normal range 200–400 mg/dL (2–4 g/L SI). Specimen: Plasma (sodium citrate).

Also known as: factor I.

200–400 mg/dLCritical: read below

Reference range

Conventionalmg/dL
200400
SIg/L
24
SpecimenPlasma (sodium citrate)
Conventional range200–400 mg/dL
SI range2–4 g/L
Conversion factor×0.01 (conventional → SI)
Critical value< 100 mg/dL (bleeding risk)
PanelCoagulation Studies

Convert any Fibrinogen result between units on the unit converter.

What is the normal range for Fibrinogen?

The standard teaching reference range for Fibrinogen is 200–400 mg/dL in conventional units, or 2–4 g/L in SI units. This value is measured in plasma (sodium citrate).

A commonly taught critical (panic) value is < 100 mg/dL (bleeding risk). Critical results are reported to the provider immediately under your facility's policy.

Source: Adult reference values compiled from Pagana & Pagana, Mosby's Diagnostic and Laboratory Test Reference, and Fischbach & Dunning, A Manual of Laboratory and Diagnostic Tests. Reference ranges vary by laboratory, method, age, sex, and population — always use the range printed on the actual result.

Above the range

Common causes of a high Fibrinogen

  • Acute inflammation (acute-phase reactant)
  • Pregnancy
  • Infection

Below the range

Common causes of a low Fibrinogen

  • DIC (consumption)
  • Liver failure
  • Massive transfusion
  • Fibrinolytic therapy

At the bedside

Nursing considerations

  • Falls in DIC as clotting factors are consumed — a useful DIC marker.

Study aid

Your notes on Fibrinogen

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