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Coagulation Studies

International Normalized Ratio (INR)

Normal range 0.8–1.1 (off anticoagulation) ratio (0.8–1.1 ratio SI). Specimen: Plasma (sodium citrate).

Also known as: INR.

0.8–1.1 (off anticoagulation) ratioCritical: read below

Reference range

Conventionalratio
0.81.1
SIratio
0.81.1
SpecimenPlasma (sodium citrate)
Conventional range0.8–1.1 (off anticoagulation) ratio
SI range0.8–1.1 ratio
Conversion factor×1 (conventional → SI)
Critical value> 5.0 (high spontaneous bleeding risk)
PanelCoagulation Studies

Convert any International Normalized Ratio (INR) result between units on the unit converter.

What is the normal range for International Normalized Ratio (INR)?

The standard teaching reference range for International Normalized Ratio (INR) is 0.8–1.1 (off anticoagulation) ratio in conventional units, or 0.8–1.1 ratio in SI units. This value is measured in plasma (sodium citrate).

A commonly taught critical (panic) value is > 5.0 (high spontaneous bleeding risk). Critical results are reported to the provider immediately under your facility's policy.

Source: Adult reference values compiled from Pagana & Pagana, Mosby's Diagnostic and Laboratory Test Reference, and Fischbach & Dunning, A Manual of Laboratory and Diagnostic Tests. Reference ranges vary by laboratory, method, age, sex, and population — always use the range printed on the actual result.

Above the range

Common causes of a high International Normalized Ratio (INR)

  • Warfarin
  • Liver disease
  • Vitamin K deficiency
  • DIC

Below the range

Common causes of a low International Normalized Ratio (INR)

  • Subtherapeutic anticoagulation
  • Vitamin K–rich diet while on warfarin

At the bedside

Nursing considerations

  • Standardizes the PT across labs; therapeutic range is usually 2.0–3.0 (2.5–3.5 for mechanical valves).
  • Hold warfarin and notify the provider for a high INR with bleeding.

Study aid

Your notes on International Normalized Ratio (INR)

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