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Liver Function (LFTs)

Alkaline Phosphatase (ALP)

Normal range 44–147 U/L (0.73–2.45 µkat/L SI). Specimen: Serum.

Also known as: alk phos.

44–147 U/LReference range

Reference range

ConventionalU/L
44147
SIµkat/L
0.732.45
SpecimenSerum
Conventional range44–147 U/L
SI range0.73–2.45 µkat/L
Conversion factor×0.0167 (conventional → SI)
PanelLiver Function (LFTs)

Convert any Alkaline Phosphatase (ALP) result between units on the unit converter.

What is the normal range for Alkaline Phosphatase (ALP)?

The standard teaching reference range for Alkaline Phosphatase (ALP) is 44–147 U/L in conventional units, or 0.73–2.45 µkat/L in SI units. This value is measured in serum.

Source: Adult reference values compiled from Pagana & Pagana, Mosby's Diagnostic and Laboratory Test Reference, and Fischbach & Dunning, A Manual of Laboratory and Diagnostic Tests. Reference ranges vary by laboratory, method, age, sex, and population — always use the range printed on the actual result.

Above the range

Common causes of a high Alkaline Phosphatase (ALP)

  • Biliary obstruction (cholestasis)
  • Bone growth or disease (Paget, mets)
  • Pregnancy
  • Liver disease

Below the range

Common causes of a low Alkaline Phosphatase (ALP)

  • Malnutrition
  • Hypothyroidism
  • Zinc deficiency

At the bedside

Nursing considerations

  • Comes from liver and bone; a high GGT confirms a hepatobiliary source.
  • Physiologically high in growing children and pregnancy.

Study aid

Your notes on Alkaline Phosphatase (ALP)

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