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What is the normal range for Mean Corpuscular Hemoglobin Concentration (MCHC)?
The standard teaching reference range for Mean Corpuscular Hemoglobin Concentration (MCHC) is 32–36 g/dL in conventional units, or 320–360 g/L in SI units. This value is measured in whole blood (edta).
Source: Adult reference values compiled from Pagana & Pagana, Mosby's Diagnostic and Laboratory Test Reference, and Fischbach & Dunning, A Manual of Laboratory and Diagnostic Tests. Reference ranges vary by laboratory, method, age, sex, and population — always use the range printed on the actual result.
Above the range
Common causes of a high Mean Corpuscular Hemoglobin Concentration (MCHC)
Hereditary spherocytosis
Marked hemolysis (sometimes artifact)
Below the range
Common causes of a low Mean Corpuscular Hemoglobin Concentration (MCHC)
Iron deficiency
Thalassemia (hypochromia)
At the bedside
Nursing considerations
A high MCHC is uncommon and often signals spherocytosis or a spurious result.
Study aid
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