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What is the normal range for Red Blood Cell Count (RBC)?
The standard teaching reference range for Red Blood Cell Count (RBC) is 4.2–5.9 10⁶/µL in conventional units, or 4.2–5.9 10¹²/L in SI units. This value is measured in whole blood (edta).
Source: Adult reference values compiled from Pagana & Pagana, Mosby's Diagnostic and Laboratory Test Reference, and Fischbach & Dunning, A Manual of Laboratory and Diagnostic Tests. Reference ranges vary by laboratory, method, age, sex, and population — always use the range printed on the actual result.
Above the range
Common causes of a high Red Blood Cell Count (RBC)
Polycythemia vera
Chronic hypoxia (COPD, high altitude)
Dehydration (relative rise)
Erythropoietin excess
Below the range
Common causes of a low Red Blood Cell Count (RBC)
Anemia of any cause
Acute or chronic blood loss
Hemolysis
Bone marrow failure
At the bedside
Nursing considerations
Men run higher than women; use sex-specific ranges when reported.
Interpret alongside hemoglobin, hematocrit, and the RBC indices.
Typical ranges: men ~4.7–6.1 and women ~4.2–5.4 × 10¹²/L.