Vitamin D, 25-Hydroxy

Normal range 30–100 sufficient (< 20 deficient) ng/mL (75–250 nmol/L SI). Specimen: Serum.

Also known as: 25-OH vitamin D, calcidiol.

30–100 sufficient (< 20 deficient) ng/mLReference range

Reference range

Conventionalng/mL

30100

SInmol/L

75250

Specimen	Serum
Conventional range	30–100 sufficient (< 20 deficient) ng/mL
SI range	75–250 nmol/L
Conversion factor	×2.496 (conventional → SI)
Panel	Inflammatory & Other Chemistry

Convert any Vitamin D, 25-Hydroxy result between units on the unit converter.

What is the normal range for Vitamin D, 25-Hydroxy?

The standard teaching reference range for Vitamin D, 25-Hydroxy is 30–100 sufficient (< 20 deficient) ng/mL in conventional units, or 75–250 nmol/L in SI units. This value is measured in serum.

Source: Adult reference values compiled from Pagana & Pagana, Mosby's Diagnostic and Laboratory Test Reference, and Fischbach & Dunning, A Manual of Laboratory and Diagnostic Tests. Reference ranges vary by laboratory, method, age, sex, and population — always use the range printed on the actual result.

Above the range

Common causes of a high Vitamin D, 25-Hydroxy

Excess supplementation (toxicity)
Rarely, granulomatous disease

Below the range

Common causes of a low Vitamin D, 25-Hydroxy

Limited sun exposure
Malabsorption
Chronic kidney or liver disease
Older age

At the bedside

Nursing considerations

The best marker of vitamin D stores; deficiency contributes to bone loss.
< 20 ng/mL is deficient, 20–29 insufficient, ≥ 30 sufficient.

Study aid

Your notes on Vitamin D, 25-Hydroxy

Your notes

Same panel

More Inflammatory & Other Chemistry tests

Amylase30–110 U/L C-Reactive Protein (CRP)< 1.0 (varies) mg/dL Erythrocyte Sedimentation Rate (ESR)≤ 20 (age/sex-dependent) mm/hr Folate (Folic Acid)3–17 ng/mL Lactate (Lactic Acid)0.5–2.2 mmol/L Lipase0–160 U/L