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Therapeutic Drug Levels

Salicylate Level

Normal range 15–30 (anti-inflammatory) mg/dL (1.1–2.2 mmol/L SI). Specimen: Serum.

Also known as: aspirin level, ASA level.

15–30 (anti-inflammatory) mg/dLCritical: read below

Reference range

Conventionalmg/dL
1530
SImmol/L
1.12.2
SpecimenSerum
Conventional range15–30 (anti-inflammatory) mg/dL
SI range1.1–2.2 mmol/L
Conversion factor×0.0724 (conventional → SI)
Critical value> 40–50 mg/dL (tinnitus, tachypnea, acid–base disturbance)
PanelTherapeutic Drug Levels

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What is the normal range for Salicylate Level?

The standard teaching reference range for Salicylate Level is 15–30 (anti-inflammatory) mg/dL in conventional units, or 1.1–2.2 mmol/L in SI units. This value is measured in serum.

A commonly taught critical (panic) value is > 40–50 mg/dL (tinnitus, tachypnea, acid–base disturbance). Critical results are reported to the provider immediately under your facility's policy.

Source: Adult reference values compiled from Pagana & Pagana, Mosby's Diagnostic and Laboratory Test Reference, and Fischbach & Dunning, A Manual of Laboratory and Diagnostic Tests. Reference ranges vary by laboratory, method, age, sex, and population — always use the range printed on the actual result.

Above the range

Common causes of a high Salicylate Level

  • Overdose
  • Chronic excess dosing

At the bedside

Nursing considerations

  • Toxicity causes tinnitus and a mixed respiratory alkalosis with metabolic acidosis; monitor ABGs.

Study aid

Your notes on Salicylate Level

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