Convert any Valproic Acid Level result between units on the unit converter.
What is the normal range for Valproic Acid Level?
The standard teaching reference range for Valproic Acid Level is 50–100 µg/mL in conventional units, or 347–693 µmol/L in SI units. This value is measured in serum (trough).
A commonly taught critical (panic) value is > 100–150 µg/mL (sedation, tremor). Critical results are reported to the provider immediately under your facility's policy.
Source: Adult reference values compiled from Pagana & Pagana, Mosby's Diagnostic and Laboratory Test Reference, and Fischbach & Dunning, A Manual of Laboratory and Diagnostic Tests. Reference ranges vary by laboratory, method, age, sex, and population — always use the range printed on the actual result.
Above the range
Common causes of a high Valproic Acid Level
Excess dosing
Liver disease
Drug interactions
Below the range
Common causes of a low Valproic Acid Level
Nonadherence
Enzyme induction
At the bedside
Nursing considerations
Monitor liver function, ammonia, and platelets; valproate can cause hepatotoxicity and thrombocytopenia.